5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 381175-08-2
| CAS No. | 381175-08-2 |
| Molecular Formula | C12H10F3N3O3 |
| Molecular Weight | 301.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid.
5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 381175-08-2) is a high-purity analytical reference standard with the molecular formula C12H10F3N3O3 and a molecular weight of 301.22 g/mol.
Structurally, 5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C12H10F3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 301.22 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3O3 |
| Molecular Weight | 301.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Furan Standards
- 2,3-Di(furan-2-yl)quinoxaline (CAS 57490-73-0)
- Methyl 2-[4-(furan-2-carbonyl)-3,4-dihydro-2H-1,4-benzoxazin-3-yl]acetate (CAS 439107-26-3)
- N-(Furan-2-ylmethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine (CAS 1218790-00-1)
- 5-(Furan-2-yl)-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole (CAS 1171771-38-2)
- N-(Furan-2-ylmethyl)-2-(pyrimidin-2-ylamino)thiazole-4-carboxamide (CAS 1251564-16-5)
- N-((5-(Furan-2-carbonyl)thiophen-2-yl)methyl)furan-2-carboxamide (CAS 1797964-08-9)
- 2-{[5-(furan-2-yl)-4-phenyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 307327-52-2)
- Furan-2-ylmethyl 3,6-dichloro-2-methoxybenzoate (CAS 33618-86-9)
Recommended Standards
- 2-Bromo-9,9-diethylfluorene (CAS 287493-15-6)
- 5-Amino-3-methyl-N-(4-(trifluoromethoxy)phenyl)isoxazole-4-carboxamide (CAS 524036-08-6)
- ((2-((5-Bromopentyl)oxy)ethoxy)methyl)benzene (CAS 956235-50-0)
- 5-Methyl-4-((3-(trifluoromethyl)phenoxy)methyl)isoxazole-3-carboxylic acid (CAS 886503-10-2)
- 3-Hydrazinylquinoline dihydrochloride (CAS 61621-35-0)
- 4-Methoxy-2-(prop-2-en-1-yloxy)benzoic acid (CAS 668455-70-7)
- Benzyl ((3-methylazetidin-3-yl)methyl)carbamate hydrochloride (CAS 1951444-33-9)
- 1-Bromo-2-(methoxymethyl)cyclohex-1-ene (CAS 929033-31-8)
- 3-Amino-2-(piperidin-1-yl)propanoic acid (CAS 1508402-18-3)
- Dihydrotriazine (CAS 1347860-96-1)
- 2-Amino-5-(naphthalen-2-ylsulfonyl)quinazolin-4(1H)-one (CAS 50828-21-2)
- 2,3-Diamino-6-(difluoromethyl)-4-methoxypyridine (CAS 1805042-93-6)
- 2-[4-(2,4-Dimethoxyphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetonitrile (CAS 861206-36-2)
- [α-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226159)
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