4-((2-Chlorobenzyl)oxy)-3-methoxybenzoyl chloride CAS 381205-83-0
| CAS No. | 381205-83-0 |
| Molecular Formula | C15H12Cl2O3 |
| Molecular Weight | 311.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-((2-Chlorobenzyl)oxy)-3-methoxybenzoyl chloride (C15H12Cl2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 311.16 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-((2-Chlorobenzyl)oxy)-3-methoxybenzoyl chloride (CAS 381205-83-0) is a high-purity analytical reference standard with the molecular formula C15H12Cl2O3 and a molecular weight of 311.16 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12Cl2O3 |
| Molecular Weight | 311.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chlorobenzyl Standards
- 2-[(2-Chlorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 1160249-83-1)
- 2-[(4-Chlorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 1160249-90-0)
- 4-[(3-Chlorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 1160250-11-2)
- 2-[(3-Chlorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 1160250-15-6)
- 4-[(4-Chlorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 293738-24-6)
- 2-((3-Chlorobenzyl)thio)-5-(2-hydroxyethyl)-6-methylpyrimidin-4-ol (CAS 338401-86-8)
- 2-((2-Chlorobenzyl)sulfonyl)benzoic acid (CAS 951911-81-2)
- 2-[(4-Chlorobenzyl)sulfonyl]benzoic acid (CAS 25700-39-4)
Recommended Standards
- 4-((2,6-Dichlorophenoxy)methyl)benzohydrazide (CAS 861414-79-1)
- 4-((3,4-Dichlorobenzyl)oxy)benzohydrazide (CAS 477845-60-6)
- 4-((2,6-Dichlorobenzyl)oxy)-3-methoxybenzaldehyde (CAS 529513-66-4)
- 4-(2,3-Dichlorobenzoyl)-N,1-dimethyl-1H-pyrrole-2-carboxamide (CAS 338753-47-2)
- 2-Amino-N-ethylbenzamide (CAS 32212-29-6)
- Benzyl 3-hydroxy-2-(Hydroxymethyl)-2-methylpropanoate (CAS 179388-73-9)
- (<I>R</I>)-(-)-1-Cbz-3-hydroxypyrrolidine (CAS 100858-33-1)
- Etomidate Impurity 32（Mixture of Diastereoisomer） (CAS CATO-C4X-188432)
- Ethyl 5-amino-4-methylisoxazole-3-carboxylate (CAS 87529-17-7)
- Darapladib (CAS 356057-34-6)
- 5-Bromo-1H-1,2,3-triazole-4-d (CAS 1643543-43-4)
- Ald-Ph-amido-PEG3-C2-NH2 (CAS 1404111-56-3)
- 1-Buten-3-ol (CAS 598-32-3)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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