N-(2-chloroethyl)-5-fluoro-2-methylbenzenesulfonamide CAS 381241-82-3

Purity 97%+In StockPharmaceutical Standards
CAS No.381241-82-3
Molecular FormulaC9H11ClFNO2S
Molecular Weight251.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-chloroethyl)-5-fluoro-2-methylbenzenesulfonamide CAS 381241-82-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 251.71 g/mol gives N-(2-chloroethyl)-5-fluoro-2-methylbenzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(2-chloroethyl)-5-fluoro-2-methylbenzenesulfonamide (CAS 381241-82-3), molecular formula C9H11ClFNO2S and molecular weight 251.71 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(2-chloroethyl)-5-fluoro-2-methylbenzenesulfonamide (C9H11ClFNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(2-chloroethyl)-5-fluoro-2-methylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H11ClFNO2S
Molecular Weight251.71 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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