5-Fluoro-2-phenylsulfonylnitrobenzene CAS 381666-56-4
| CAS No. | 381666-56-4 |
| Molecular Formula | C12H8FNO4S |
| Molecular Weight | 281.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoro-2-phenylsulfonylnitrobenzene.
5-Fluoro-2-phenylsulfonylnitrobenzene (CAS 381666-56-4), molecular formula C12H8FNO4S and molecular weight 281.26 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H8FNO4S, 5-Fluoro-2-phenylsulfonylnitrobenzene contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 281.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoro-2-phenylsulfonylnitrobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8FNO4S |
| Molecular Weight | 281.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
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- Bendamustine Impurity 25 (CAS 91644-13-2)
- Methyl 6-chloro-5-(trifluoromethyl)picolinate (CAS 1211518-35-2)
- N-allyl-2-(3-chlorobenzoyl)hydrazine-1-carbothioamide (CAS 15944-95-3)
- N-(4-(N-((1-Cyclopentyl-5-(thiophen-2-yl)-1H-pyrazol-3-yl)methyl)sulfamoyl)phenyl)acetamide (CAS 1421514-45-5)
- 2,4-Dimethyl-1,5-diphenylcyclopent-4-ene-1,3-diol (CAS 5141-38-8)
- DNP-NH-PEG-acid (CAS 1334178-00-5)
- 2-(2-Acetylphenyl)-2-hydroxyacetic acid (CAS 1003707-95-6)
- N-((1-((S)-2-Aminopropanoyl)pyrrolidin-3-yl)methyl)acetamide (CAS 1354033-49-0)
- Dequalinium Impurity 7 (CAS 19056-26-9)
- 1-(2,6-Difluorophenyl)cyclopentanemethanamine (CAS 1235439-03-8)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
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