4,6-dichloro-2-fluoro-pyrimidine CAS 3824-45-1

Purity 97%+In StockPharmaceutical Standards
CAS No.3824-45-1
Molecular FormulaC4H7Cl2FN2
Molecular Weight173.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,6-dichloro-2-fluoro-pyrimidine CAS 3824-45-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 173.02 g/mol gives 4,6-dichloro-2-fluoro-pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4,6-dichloro-2-fluoro-pyrimidine (CAS 3824-45-1), a certified reference material (molecular formula C4H7Cl2FN2, MW 173.02 g/mol) for analytical method development and quality control.

The molecular framework of 4,6-dichloro-2-fluoro-pyrimidine (C4H7Cl2FN2) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H7Cl2FN2
Molecular Weight173.02 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1958
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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