1-(Chloromethyl)-2-fluoronaphthalene CAS 3825-14-7
| CAS No. | 3825-14-7 |
| Molecular Formula | C11H8ClF |
| Molecular Weight | 194.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(Chloromethyl)-2-fluoronaphthalene (CAS 3825-14-7) is a high-purity analytical reference standard with the molecular formula C11H8ClF and a molecular weight of 194.63 g/mol.
Owing to fluorine/chlorine substitution, an aromatic ring system, 1-(Chloromethyl)-2-fluoronaphthalene is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 194.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-(Chloromethyl)-2-fluoronaphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF |
| Molecular Weight | 194.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-6-fluoronaphthalene (CAS 1261690-64-5)
- 1-(Chloromethyl)-4-fluoronaphthalene (CAS 3094-25-5)
- 2-[4-(Chloromethyl)-1,3-oxazol-2-yl]pyridine (CAS 1009563-22-7)
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Recommended Standards
- (4-Chlorophenyl)(difluoromethyl)sulfane (CAS 2488-66-6)
- (4-Chloro-2,3-difluorophenyl)(methyl)sulfane (CAS 1807125-31-0)
- Copper, (L-aspartato)- (CAS 30272-90-3)
- 3-Chloro-2,6-difluorothioanisole (CAS 1428234-53-0)
- Ethyl 3-(3-fluorophenyl)acrylate (CAS 351-46-2)
- 1-((2,4-Dichlorobenzyl)sulfonyl)-2-(3,4-dichlorophenyl)propan-2-ol (CAS 339276-85-6)
- N-(thiazol-2-yl)pyrrolidine-2-carboxamide (CAS 787498-56-0)
- 3-Methyl-2,3,4,4a,9,9a-hexahydro-1H-carbazole (CAS 6731-87-9)
- Methyl (R)-2-(2-chloroethyl)-4,4-difluoropyrrolidine-2-carboxylate (CAS 2820537-47-9)
- 3,5-Bis(trimethylsilyl)isonicotinonitrile (CAS 827616-49-9)
- 4-(Methoxyamino-methyl)-benzoic acid methyl ester (CAS 543731-23-3)
- Ozenoxacin Impurity 72 (CAS CATO-C4X-279672)
- Allyl(3-chloro-5-fluorophenyl)sulfane (CAS 1379342-76-3)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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