2,2-Difluoro-2-phenylacetamide CAS 383-19-7
| CAS No. | 383-19-7 |
| Molecular Formula | C8H7F2NO |
| Molecular Weight | 171.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,2-Difluoro-2-phenylacetamide (CAS 383-19-7), a certified reference material (molecular formula C8H7F2NO, MW 171.14 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2,2-Difluoro-2-phenylacetamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 171.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2,2-Difluoro-2-phenylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F2NO |
| Molecular Weight | 171.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- (R)-5,7-Difluoro-2,3-dihydrobenzofuran-3-amine (CAS 1213895-29-4)
- (S)-5,7-Difluoro-2,3-dihydrobenzofuran-3-amine (CAS 1241676-95-8)
- 2,3-Difluoro-N-methylbenzamide (CAS 1250397-72-8)
- (R)-6,7-Difluoro-2,3-dihydrobenzofuran-3-amine (CAS 1259759-12-0)
- (S)-6,7-Difluoro-2,3-dihydrobenzofuran-3-amine (CAS 1259857-64-1)
- 6,7-Difluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1267772-25-7)
- (R)-5,6-Difluoro-2,3-dihydrobenzofuran-3-amine (CAS 1272739-50-0)
- 3,5-Difluoro-2-methylbenzamide (CAS 1323966-37-5)
Recommended Standards
- 2,2-Difluoro-2,3-dihydrobenzofuran-5-amine (CAS 2803883-37-4)
- 2,3-Difluoro-4-methylbenzamide (CAS 261763-35-3)
- 2-(3,4-Difluorophenyl)acetamide (CAS 861393-53-5)
- 2,4-Difluoro-N-methylbenzamide (CAS 948717-18-8)
- 3-Methyl-1-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butan-1-one (CAS 2377609-74-8)
- Ethyl 2-(3-chloro-2-oxopyrazin-1(2H)-yl)acetate (CAS 435345-05-4)
- 2-amino-1-(pyridin-2-yl)propane-1,3-diol dihydrochloride (CAS 2060024-55-5)
- 8-Methoxy-3,4-dihydroquinoxalin-2(1H)-one (CAS 1566145-35-4)
- 4-chloro-N-(2,5-dioxo-7,8-dihydro-6H-chromen-3-yl)benzamide (CAS 338404-90-3)
- 2-Iodyl-4-nitrobenzoic acid (CAS 112391-35-2)
- Ethyl 2-[1-(4-nitrophenyl)-4-piperidinylidene]acetate (CAS 251310-52-8)
- 8,8-Difluoro-6-azaspiro[2.5]octane (CAS 1282657-03-7)
- N-(2,5-Difluorobenzyl)-1,5-dimethyl-1H-pyrazol-4-amine hydrochloride (CAS 1856053-87-6)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com