N-(4-ethynylphenyl)-2-fluorobenzenesulfonamide CAS 383147-79-3
| CAS No. | 383147-79-3 |
| Molecular Formula | C14H10FNO2S |
| Molecular Weight | 275.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-(4-ethynylphenyl)-2-fluorobenzenesulfonamide (CAS 383147-79-3) is a high-purity analytical reference standard with the molecular formula C14H10FNO2S and a molecular weight of 275.30 g/mol.
The molecular framework of N-(4-ethynylphenyl)-2-fluorobenzenesulfonamide (C14H10FNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures N-(4-ethynylphenyl)-2-fluorobenzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10FNO2S |
| Molecular Weight | 275.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-ethynylphenyl)-4-fluorobenzenesulfonamide (CAS 691873-32-2)
- n-(3-Ethynylphenyl)-4-methylbenzenesulfonamide (CAS 860788-60-9)
- 2,4-Bis(4-ethynylphenyl)pyridine (CAS 1285694-84-9)
- 2-(4-Ethynylphenyl)-2,3-dihydro-1h-naphtho[1,8-de][1,3,2]diazaborinine (CAS 2301919-15-1)
- ((4-Ethynylphenyl)ethynyl)triisopropylsilane (CAS 175345-90-1)
- 9-(4-Ethynylphenyl)-9H-carbazole (CAS 262861-81-4)
- N-(3-Ethynylphenyl)-3-(trifluoromethyl)benzamide (CAS 1016435-75-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com