2,4-Dichloro-6-methylnicotinonitrile CAS 38367-36-1
| CAS No. | 38367-36-1 |
| Molecular Formula | C7H4Cl2N2 |
| Molecular Weight | 187.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4-Dichloro-6-methylnicotinonitrile is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,4-Dichloro-6-methylnicotinonitrile (CAS 38367-36-1) is a high-purity analytical reference standard with the molecular formula C7H4Cl2N2 and a molecular weight of 187.03 g/mol.
The molecular framework of 2,4-Dichloro-6-methylnicotinonitrile (C7H4Cl2N2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2N2 |
| Molecular Weight | 187.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- (R)-2-(Piperazin-2-yl)ethan-1-oldihydrochloride (CAS 1565818-62-3)
- n-(3-Ethoxypropyl)thieno[2,3-d]pyrimidin-4-amine (CAS 728941-59-1)
- 2-(Cyclobutylmethoxy)pyrimidine-4-carboxylic acid (CAS 2091952-95-1)
- CAS 2260670-48-0 (CAS 2260670-48-0)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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