2-Amino-6-chlorobenzene-1-thiol hydrochloride CAS 385376-58-9
| CAS No. | 385376-58-9 |
| Molecular Formula | C6H6ClNS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Amino-6-chlorobenzene-1-thiol hydrochloride is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Amino-6-chlorobenzene-1-thiol hydrochloride (CAS 385376-58-9) is a high-purity analytical reference standard with the molecular formula C6H6ClNSHCl and a molecular weight of 196.09 g/mol.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, 2-Amino-6-chlorobenzene-1-thiol hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 196.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNS HCl |
| Molecular Weight | 196.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-1-methyl-4-phenoxyindazole (CAS 1000018-07-4)
- 3-Amino-2,6-dibromo-5-ethoxypyridine (CAS 1000018-10-9)
- Methyl 2-amino-5-bromo-4-isopropylbenzoate (CAS 1000018-13-2)
- Methyl 2-amino-3-(pyridin-2-yl)propanoate (CAS 100002-84-4)
- 100005-23-0 2-Amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carbonitrile 7050AC C13H12N2OS (CAS 100005-23-0)
- Methyl 1-amino-4-cyano-1H-pyrrole-2-carboxylate (CAS 1000313-12-1)
- 6-Amino-7-hydroxy-2,3-dihydro-1H-inden-1-one hydrobromide (CAS 1000333-87-8)
- 6-Amino-7-iodo-2,3-dihydro-1H-inden-1-one (CAS 1000333-93-6)
Recommended Standards
- Methyl 4-methyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate (CAS 1616506-65-0)
- 3,5-Di-tert-butyl-[1,1'-biphenyl]-4-ol (CAS 2668-47-5)
- 1-(4-Aminophenyl)-4-[3-(trifluoromethyl)phenyl]piperazine (CAS 886843-56-7)
- 6-Methyl-2-(pyrrolidin-1-yl)pyrimidine-4-carboxylic acid (CAS 1017422-68-2)
- Methyl 3-{[(pyridin-4-yl)methyl]amino}butanoate (CAS 1154385-60-0)
- Atosiban Impurity 31 (CAS CATO-C4X-229331)
- 3,6-Dicyclopropyl-1-{[(propan-2-yl)carbamoyl]methyl}-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018052-23-7)
- 6-Amino-1H-naphtho[1,2-d]imidazol-2(3H)-one (CAS 155137-75-0)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com