4-Benzyl 1-(tert-butyl) (S)-2-(hydroxymethyl)piperazine-1,4-dicarboxylate CAS 385802-84-6
| CAS No. | 385802-84-6 |
| Molecular Formula | C18H26N2O5 |
| Molecular Weight | 350.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Benzyl 1-(tert-butyl) (S)-2-(hydroxymethyl)piperazine-1,4-dicarboxylate (CAS 385802-84-6), molecular formula C18H26N2O5 and molecular weight 350.41 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Benzyl 1-(tert-butyl) (S)-2-(hydroxymethyl)piperazine-1,4-dicarboxylate (C18H26N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H26N2O5 |
| Molecular Weight | 350.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 4-Benzyl 1-(tert-butyl) (R)-2-(hydroxymethyl)piperazine-1,4-dicarboxylate (CAS 930782-89-1)
- 4-Butyl-5-oxo-1,2-diphenyl-2,5-dihydro-1H-pyrazol-3-yl acetate (CAS 57091-22-2)
- 4-[4-(9h-fluoren-9-yl)piperazin-1-yl]-4-oxobutanoic acid (CAS 714201-06-6)
- 4-Hydroxy-1-methyl-N-(p-tolyl)-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide (CAS 303987-79-3)
- (1R)-1-(3-hydroxyphenyl)ethane-1,2-diol (CAS 158551-93-0)
- 4-Amino-3-methoxy-5-nitrobenzonitrile (CAS 77333-46-1)
- 3-(Difluoromethyl)-5-hydroxypicolinonitrile (CAS 1804759-34-9)
- 4-((((1-(2-Fluoroethyl)-1H-pyrazol-5-yl)methyl)amino)methyl)-2-methoxyphenol hydrochloride (CAS 1856057-48-1)
- Methyl 1-(5-bromopyrimidin-2-yl)cyclopropanecarboxylate (CAS 1447607-69-3)
- N-(m-tolyl)acrylamide (CAS 17208-98-9)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with ethenyl acetate and ethenylbenzene (CAS 25750-33-8)
- (2-Chloroethyl)cycloheptane (CAS 84226-37-9)
- sodium5-[(aminocarbonyl)hydrazono]-2,3,5,6-tetrahydro-1-methyl-6-oxo-1H-indole-3-sulphonate (CAS 1428-72-4)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com