3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one CAS 386-17-4
| CAS No. | 386-17-4 |
| Molecular Formula | C20H10I4O4 |
| Molecular Weight | 821.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one (CAS 386-17-4), molecular formula C20H10I4O4 and molecular weight 821.91 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one (C20H10I4O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H10I4O4 |
| Molecular Weight | 821.91 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | I-containing |
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