4,6-Bis(trifluoromethyl)pyridin-2(1H)-one CAS 38609-77-7
| CAS No. | 38609-77-7 |
| Molecular Formula | C7H3F6NO |
| Molecular Weight | 231.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,6-Bis(trifluoromethyl)pyridin-2(1H)-one (C7H3F6NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4,6-Bis(trifluoromethyl)pyridin-2(1H)-one (CAS 38609-77-7), molecular formula C7H3F6NO and molecular weight 231.10 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,6-Bis(trifluoromethyl)pyridin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3F6NO |
| Molecular Weight | 231.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 3,5-Bis-trifluoromethyl-1h-pyridin-4-one (CAS 1063697-13-1)
- 3,6-Bis(trifluoromethyl)pyrazin-2-amine (CAS 1803601-40-2)
- 3,5-Bis(trifluoromethyl)pyrazin-2-amine (CAS 1823898-82-3)
- 2,6-Bis(trifluoromethyl)pyridin-4-ol (CAS 43150-55-6)
- 3,5-Bis(trifluoromethyl)pyridin-2-ol (CAS 38609-76-6)
- 2-(Trifluoromethyl)-1,3-benzoxazole-6-carboxylic acid (CAS 1181288-08-3)
- 6-(Trifluoromethyl)-2,1-benzoxazole-3-carboxylic acid (CAS 1204298-47-4)
- 8-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1210246-41-5)
Recommended Standards
- 4-(3,4-Dichlorophenyl)-1,2,3-thiadiazole (CAS 94843-30-8)
- 4,6-Dichloro-2-(thiophen-2-yl)pyrimidine (CAS 57059-13-9)
- 3-Chloro-6-(5-chlorothiophen-2-yl)pyridazine (CAS 75792-71-1)
- 4,6-Dichloro-2-(thiophen-3-yl)pyrimidine (CAS 57059-14-0)
- Tert-butyl 7-cyano-3-azaspiro[5.5]Undecane-3-carboxylate (CAS 2306260-96-6)
- 2-(4-amino-1-benzylpiperidin-4-yl)acetic acid (CAS 1023471-40-0)
- 4-Iodo-6-oxabicyclo[3.2.1]octan-7-one (CAS 76140-13-1)
- 3,3-Bis(4-methoxybenzyl)pent-4-en-1-ol (CAS 1384881-63-3)
- 6-(2,2,2-Trifluoroethoxy)pyridine-3-carbonitrile (CAS 159981-18-7)
- N-Mal-N-bis(PEG4-NH-Boc) (CAS 2128735-27-1)
- (R)-O-(Pyrrolidin-2-ylmethyl)hydroxylaminedihydrochloride (CAS 952747-32-9)
- 3-(2,6-Dichlorophenyl)-4-(4-phenoxybenzoyl)-1,2-oxazole (CAS 338411-90-8)
- 3-(4-Aminophenyl)-1-(4-methylphenyl)propan-1-ol (CAS 87082-25-5)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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