5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-quinazolin-6-yl)furan-2-carbaldehyde hydrochloride CAS 388082-76-6
| CAS No. | 388082-76-6 |
| Molecular Formula | C26H17ClFN3O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-quinazolin-6-yl)furan-2-carbaldehyde hydrochloride (CAS 388082-76-6) is a high-purity analytical reference standard with the molecular formula C26H17ClFN3O3HCl and a molecular weight of 510.35 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-quinazolin-6-yl)furan-2-carbaldehyde hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 510.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-quinazolin-6-yl)furan-2-carbaldehyde hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H17ClFN3O3 HCl |
| Molecular Weight | 510.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 3-[(2-Chloro-4-methylsulfonyl)phenoxy]benzoic acid (CAS 1000018-31-4)
- 6-Chloro-2-[2-(3-[(6-chloro-1-ethylbenz[c,d,]indole-2[1H]-ylidene)ethylidene]-2-phenyl-1-cyclopenten-1-yl)ethenyl]-1-ethylbenz[c,d]indolium tetrafluoroborate (CAS 100012-45-1)
- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
- (3-Chloro-2-fluoro-5-iodophenyl)methanol (CAS 1000162-10-6)
- 3-Chloro-2-fluoro-5-nitrobenzoic acid (CAS 1000162-34-4)
- 2-Chloro-N-(piperidin-4-yl)-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-amine hydrochloride (CAS 1000207-51-1)
- 4-chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine (CAS 1000303-40-1)
Recommended Standards
- Tert-butyl (2-(2-aminophenoxy)ethyl)carbamate (CAS 263410-16-8)
- 2-Chloro-5-((4-methylpiperazin-1-yl)methyl)thiazole (CAS 341967-70-2)
- Abediterol napadisylate, >98% (HPLC) (CAS 1044516-17-7)
- Methyl 4-bromo-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylate (CAS 1429418-54-1)
- 3-(Pyrrolidin-1-yl)adamantan-1-ol (CAS 856437-84-8)
- 7-Fluoro-2-methyl-1H-indole-5-carbonitrile (CAS 1401726-98-4)
- 4-tert-Butylcyclohexyl Acrylate (CAS 84100-23-2)
- Ethyl (tert-butoxycarbonyl)-L-cysteinate (CAS 118143-52-5)
- 3-((7-Oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)methyl)benzoic acid (CAS 1707594-84-0)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com