多奈哌齐杂质12 CAS 388115-12-6
| CAS No. | 388115-12-6 |
| Molecular Formula | C24H24NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 多奈哌齐杂质12 (C24H24NO3Cl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 409.91 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
多奈哌齐杂质12 (CAS 388115-12-6) is a certified pharmaceutical impurity reference standard with the molecular formula C24H24NO3Cl and a molecular weight of 409.91 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H24NO3 Cl |
| Molecular Weight | 409.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Cabazitaxel Impurity 12 (CAS CATO-C4X-111512)
- Moxifloxacin Impurity 67 (CAS 151213-39-7 (free base))
- Atrasentan Impurity 74 (CAS 1058540-33-2)
- Vitamin K1 Impurity 71 (CAS 2457204-51-0)
- Bis(4-methoxyphenyl)methane (CAS 726-18-1)
- 2,3,4,5-Tetrahydro-N-methoxy-7,8-dimethyl-1-benzoxepin-5-amine (CAS 1410793-09-7)
- 4-Galactosyllactose (CAS 6587-31-1)
- Descarbosy Ranelic Acid (CAS 1219692-43-9)
- N-[2-(Dimethylamino)ethyl]-9,10-dihydro-9-oxo-4-acridinecarboxamide (CAS 103554-58-1)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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