2,6-Dibromo-4-methylnicotinonitrile CAS 38824-75-8

Purity 97%+In StockPharmaceutical Standards
CAS No.38824-75-8
Molecular FormulaC7H4Br2N2
Molecular Weight275.93 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-Dibromo-4-methylnicotinonitrile CAS 38824-75-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 275.93 g/mol gives 2,6-Dibromo-4-methylnicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,6-Dibromo-4-methylnicotinonitrile (CAS 38824-75-8) is a high-purity analytical reference standard with the molecular formula C7H4Br2N2 and a molecular weight of 275.93 g/mol.

The molecular framework of 2,6-Dibromo-4-methylnicotinonitrile (C7H4Br2N2) is characterized by a nitrile group, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,6-Dibromo-4-methylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H4Br2N2
Molecular Weight275.93 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1968
Halogen ContentBr-containing
Nitrogen Atoms2

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