5-Amino-4-iodo-2-methylphenol CAS 388616-53-3
| CAS No. | 388616-53-3 |
| Molecular Formula | C7H8INO |
| Molecular Weight | 249.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-4-iodo-2-methylphenol (CAS 388616-53-3) is a high-purity analytical reference standard with the molecular formula C7H8INO and a molecular weight of 249.05 g/mol.
5-Amino-4-iodo-2-methylphenol (C7H8INO) contains an amide group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Amino-4-iodo-2-methylphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8INO |
| Molecular Weight | 249.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- (2-Amino-4-iodophenyl)methanol (CAS 1260903-21-6)
- (3-Amino-4-iodophenyl)methanol (CAS 1261521-21-4)
- (5-Amino-2-iodophenyl)methanol (CAS 1261609-99-7)
- (4-Amino-2-iodophenyl)methanol (CAS 1261645-45-7)
- (2-Amino-6-iodophenyl)methanol (CAS 1261838-16-7)
- 4-amino-3-iodoanisole (CAS 191348-14-8)
- (2-Amino-3-iodophenyl)methanol (CAS 53279-84-8)
- (3-Amino-5-iodophenyl)methanol (CAS 368435-46-5)
Recommended Standards
- 5-(Aminomethyl)-2-iodophenol (CAS 943749-98-2)
- 5-Iodo-2,6-dimethylpyrimidin-4-amine (CAS 2033-48-9)
- 4-Iodo-2-methoxyaniline (CAS 338454-80-1)
- 5-Iodo-4,6-dimethylpyrimidin-2-amine (CAS 2033-47-8)
- 2-Phenyl-2,3-dihydro-1H-isoindole-1,3-dione (CAS 520-03-6)
- 2-((4-Chlorobenzyl)thio)-4,6-bis(4-chlorophenyl)nicotinonitrile (CAS 332385-86-1)
- Methyl 4-(4-hydroxypiperidin-2-yl)benzoate (CAS 2355625-22-6)
- N-(4-Chloro-6-(methylamino)pyrimidin-2-yl)acetamide (CAS 88380-67-0)
- 3-Methoxy-N-(propan-2-yl)aniline (CAS 31143-05-2)
- Venetoclax Impurity 113 (CAS CATO-C4X-2495113)
- 1-Amino-N-methyl-cyclopentanecarboxamide (CAS 896734-86-4)
- 3-(Propylsulfanyl)-1,2,4-thiadiazol-5-amine (CAS 6913-15-1)
- Arbidol Impurity 53 (CAS CATO-C4X-112953)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
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