4-Chloro-6-methylnicotinonitrile CAS 38875-76-2
| CAS No. | 38875-76-2 |
| Molecular Formula | C7H5ClN2 |
| Molecular Weight | 152.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6-methylnicotinonitrile.
CATO supplies 4-Chloro-6-methylnicotinonitrile (CAS 38875-76-2), a certified reference material (molecular formula C7H5ClN2, MW 152.58 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-6-methylnicotinonitrile (C7H5ClN2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-6-methylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2 |
| Molecular Weight | 152.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-65-3)
- 2-(2-Chloro-4-pyridyl)acetonitrile (CAS 1000565-45-6)
- 2-(2-Chloro-3-pyridyl)acetonitrile (CAS 101012-32-2)
- 4-Chloro-2-cyano-6-methylpyridine, 97% (CAS 104711-65-1)
- Methyl 4-chloro-3-hydroxybutanoate (CAS 10488-68-3)
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- 2-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1174936-85-6)
- 4-Chloro-6-azaindole (CAS 1188313-15-6)
Recommended Standards
- 4-Amino-2-chlorobenzonitrile (CAS 20925-27-3)
- 4-Chloro-7-azaindole (CAS 55052-28-3)
- 4-(Chloromethyl)pyridine-2-carbonitrile (CAS 71935-33-6)
- 4-Chlorobenzofuran (CAS 257864-14-5)
- 1-(2-methyl-1,3-oxazol-4-yl)ethan-1-ol (CAS 1803595-56-3)
- 4-Chloro-6-(2-methyl-1-piperidinyl)-1,3,5-triazin-2-amine (CAS 1220016-66-9)
- (R)-1-Boc-2-azetidinemethanol (CAS 161511-90-6)
- Ptelatoside B (CAS 90852-99-6)
- Naphthalene-1,5-dicarbonitrile (CAS 13554-71-7)
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methyl-8-(3-methylbut-2-en-1-yl)chroman-4-one (CAS 261776-60-7)
- (E)-Methyl 3-(3-(cyclohexanecarboxamido)phenyl)acrylate (CAS 592524-89-5)
- 3-(2-(Piperidin-1-yl)ethoxy)benzoic acid (CAS 765270-93-7)
- 3-chloro-2-hydroxypropyl dihydrogen phosphate (CAS 56729-01-2)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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