[(1S,3R,4S)-5,5-Difluorodispiro[2.0.2.1]Hept-1-Yl]Methanol CAS 389873-51-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [(1S,3R,4S)-5,5-Difluorodispiro[2.0.2.1]Hept-1-Yl]Methanol.

[(1S,3R,4S)-5,5-Difluorodispiro[2.0.2.1]Hept-1-Yl]Methanol (CAS 389873-51-2) is a high-purity analytical reference standard with the molecular formula C8H10F2O and a molecular weight of 160.16 g/mol.

[(1S,3R,4S)-5,5-Difluorodispiro[2.0.2.1]Hept-1-Yl]Methanol (C8H10F2O) contains a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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