5-Chloro-N-(4-nitrophenyl)thiophene-2-carboxamide CAS 391225-52-8
| CAS No. | 391225-52-8 |
| Molecular Formula | C11H7ClN2O3S |
| Molecular Weight | 282.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-N-(4-nitrophenyl)thiophene-2-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-N-(4-nitrophenyl)thiophene-2-carboxamide (CAS 391225-52-8) is a high-purity analytical reference standard with the molecular formula C11H7ClN2O3S and a molecular weight of 282.70 g/mol.
Structurally, 5-Chloro-N-(4-nitrophenyl)thiophene-2-carboxamide (C11H7ClN2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 282.70 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClN2O3S |
| Molecular Weight | 282.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 3-Methyl-2-((2,2,2-trifluoroethoxy)methyl)butane-1-sulfonyl chloride (CAS 1486306-59-5)
- 4-Amino-N-((1-benzylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide (CAS 93839-84-0)
- 2-Hydrazinylpyrimidine-5-carbonitrile (CAS 38373-51-2)
- 3-Amino-7,8-dihydro-5H-thiopyrano[4,3-c]pyridazine 6,6-dioxide (CAS 1271639-92-9)
- 3-iodo-4-methoxy-benzoic acid hydrazide 314763-97-8 SC-42091 (CAS 314763-97-8)
- Daptomycin Impurity 42 (CAS CATO-C4X-137842)
- (pyrrolidin-3-ylmethyl)urea (CAS 1502197-40-1)
- N-(5-(2-Aminoethyl)-1H-1,2,4-triazol-3-yl)benzamide (CAS 1338495-28-5)
- 1-(4-Tert-butylphenyl)-2-methylpropan-1-one (CAS 60561-82-2)
- Ethyl cyclopropanesulfonate (CAS 2095432-70-3)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
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