N-(4-(5-Bromothiophen-2-yl)thiazol-2-yl)-3,5-dichlorobenzamide CAS 391229-64-4

Purity 97%+In StockPharmaceutical Standards
CAS No.391229-64-4
Molecular FormulaC14H7BrCl2N2OS2
Molecular Weight434.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-(5-Bromothiophen-2-yl)thiazol-2-yl)-3,5-dichlorobenzamide CAS 391229-64-4 chemical structure

Description

The occurrence of N-(4-(5-Bromothiophen-2-yl)thiazol-2-yl)-3,5-dichlorobenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(4-(5-Bromothiophen-2-yl)thiazol-2-yl)-3,5-dichlorobenzamide (CAS 391229-64-4) is a high-purity analytical reference standard with the molecular formula C14H7BrCl2N2OS2 and a molecular weight of 434.16 g/mol.

The molecular framework of N-(4-(5-Bromothiophen-2-yl)thiazol-2-yl)-3,5-dichlorobenzamide (C14H7BrCl2N2OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H7BrCl2N2OS2
Molecular Weight434.16 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl/Br-containing
Nitrogen Atoms2
Sulfur Atoms2

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