Flucloxacillin EP Impurity D CAS 3919-74-2
| CAS No. | 3919-74-2 |
| Molecular Formula | C11H7ClFNO3 |
| Molecular Weight | 255.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Flucloxacillin EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Flucloxacillin EP Impurity D (CAS 3919-74-2), a pharmacopoeial impurity reference standard (molecular formula C11H7ClFNO3, MW 255.63 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Flucloxacillin EP Impurity D (C11H7ClFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H7ClFNO3 |
| Molecular Weight | 255.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Flucloxacillin Standards
- Flucloxacillin RC 3 (CAS 1796928-46-5)
- Flucloxacillin RC 4 (CAS 1797891-06-5)
- Flucloxacillin RC 5 (CAS 1797982-77-4)
- Flucloxacillin Monohydrate EP Impurity F (CAS 866150-92-7)
- Flucloxacillin RC 6 (CAS 1797824-55-5)
- Flucloxacillin EP Impurity B (Mixture of Diastereomers) (CAS 1276016-89-7)
- Flucloxacillin EP Impurity B (CAS CATO-C4X-16472)
- Flucloxacillin - API Standards (CAS 5250-39-5)
Recommended Standards
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- Sulfasalazine EP Impurity J (CAS 144-83-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com