2-(Chloromethyl)pyrazine CAS 39204-47-2
| CAS No. | 39204-47-2 |
| Molecular Formula | C5H5ClN2 |
| Molecular Weight | 128.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)pyrazine.
2-(Chloromethyl)pyrazine (CAS 39204-47-2) is a high-purity analytical reference standard with the molecular formula C5H5ClN2 and a molecular weight of 128.56 g/mol.
2-(Chloromethyl)pyrazine (C5H5ClN2) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Chloromethyl)pyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN2 |
| Molecular Weight | 128.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 5-(Chloromethyl)pyrimidine (CAS 101346-02-5)
- 2-chloromethyl-pyrimidine (CAS 54198-88-8)
- 3-(Chloromethyl)pyridazine (CAS 41227-72-9)
- 4-(Chloromethyl)pyrimidine (CAS 54198-81-1)
- Chloromethyl chloroformate (CAS 22128-62-7)
- 2-(Chloromethyl)pyridine (CAS 4377-33-7)
- 2-(1-(Chloromethyl)cyclopropyl)acetonitrile (CAS 1936099-06-7)
- 1-(Chloromethyl)cyclobutane-1-carbonitrile (CAS 869224-45-3)
Recommended Standards
- Edoxaban Impurity 102 (CAS 19798-80-2)
- 2-Chloro-5-methylpyrazine (CAS 59303-10-5)
- 2-Chloro-4-methylpyrimidine (CAS 13036-57-2)
- 2-Chloro-5-methylpyrimidine (CAS 22536-61-4)
- 1-(Benzyloxy)-3-chloro-5-nitrobenzene (CAS 128923-98-8)
- 3-(Aminomethyl)-7-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-8(7H)-one (CAS 1707372-63-1)
- 4-Hydrazinobenzoic Acid-d4 Hydrochloride (CAS 1246816-67-0)
- Methyl 7-amino-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 691869-96-2)
- 2-(3,5-Dimethylphenyl)benzo[d]oxazole (CAS 154715-81-8)
- delta-14-Desonide (CAS 131918-67-7)
- N-([1,1'-Biphenyl]-2-yl)-2-((4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 577988-98-8)
- 2,4-Diphenyl-5,6,7,8-tetrahydrochromenylium tetrafluoroborate (CAS 53731-45-6)
- Ethyl 2-(dihydrofuran-3(2H)-ylidene)acetate (CAS 239127-73-2)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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