N-(5-Benzoyl-4-phenylthiazol-2-yl)-3-(4-nitrophenyl)acrylamide CAS 392326-01-1
| CAS No. | 392326-01-1 |
| Molecular Formula | C25H17N3O4S |
| Molecular Weight | 455.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(5-Benzoyl-4-phenylthiazol-2-yl)-3-(4-nitrophenyl)acrylamide (CAS 392326-01-1) is a high-purity analytical reference standard with the molecular formula C25H17N3O4S and a molecular weight of 455.49 g/mol.
N-(5-Benzoyl-4-phenylthiazol-2-yl)-3-(4-nitrophenyl)acrylamide (C25H17N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C25H17N3O4S |
| Molecular Weight | 455.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-(((2-(2-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)benzo[b]thiophen-5-yl)methyl)amino)propanoic acid (CAS 820240-77-5)
- XL388 (CAS 1251156-08-7)
- 2-(1-Phenyl-1H-pyrazole-4-carbonyl)phenyl quinoline-8-sulfonate (CAS 956764-05-9)
- N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S)-2,2-dimethyl-1-(1-piperidinylmethyl)propyl]thiourea (CAS 1260435-12-8)
- tert-Butyl 4-(2-amino-6-fluorophenylamino)piperidine-1-carboxylate (CAS 1004304-06-6)
- tert-Butyl ((S)-1-((S)-2-aminopropanoyl)pyrrolidin-3-yl)(methyl)carbamate (CAS 1401669-02-0)
- (3,4-Dichlorophenyl)(3,4-difluorophenyl)methanone (CAS 844885-31-0)
- 2-(2-(Trifluoromethoxy)phenyl)pyrimidine-5-carboxylic acid (CAS 1261765-94-9)
- Quinoline-3,7-dicarboxylic acid (CAS 149734-20-3)
- tert-butyl 3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylate (CAS 174180-77-9)
- 4-(Difluoromethyl)-5-nitro-3-(trifluoromethyl)pyridin-2-ol (CAS 1806971-34-5)
- 4,4,4-Trifluoro-3-(tetrahydrofuran-3-yl)butanoic acid (CAS 1342587-48-7)
- 2-(1H-benzimidazol-2-yl)-1-(2-furyl)ethanone hydrochloride (CAS 1177272-41-1)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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