N-(4-acetamidophenyl)-2,2,2-trifluoroacetamide CAS 392695-18-0
| CAS No. | 392695-18-0 |
| Molecular Formula | C10H9F3N2O2 |
| Molecular Weight | 246.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-acetamidophenyl)-2,2,2-trifluoroacetamide (C10H9F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(4-acetamidophenyl)-2,2,2-trifluoroacetamide (CAS 392695-18-0), molecular formula C10H9F3N2O2 and molecular weight 246.19 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(4-acetamidophenyl)-2,2,2-trifluoroacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9F3N2O2 |
| Molecular Weight | 246.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(3-acetamidophenyl)-2,2,2-trifluoroacetamide (CAS 194801-20-2)
- 3-(3-Acetamidophenyl)pyrazole-5-carboxylic Acid (CAS 1240061-39-5)
- n-(4-Acetamidophenyl)furan-2-carboxamide (CAS 22941-33-9)
- 4-((4-Acetamidophenyl)amino)-4-oxobut-2-enoic acid (CAS 108749-44-6)
- methyl 4-(4-acetamidophenyl)-4-oxobutanoate (CAS 1267904-73-3)
- 1-(4-Acetamidophenyl)-3-allylthiourea (CAS 17098-56-5)
- 4-((4-Acetamidophenyl)amino)-4-oxobutanoic acid (CAS 188011-68-9)
- 4-((3-Acetamidophenyl)amino)-4-oxobutanoic acid (CAS 722466-08-2)
Recommended Standards
- n-(2-Amino-2-oxoethyl)-4-(trifluoromethyl)benzamide (CAS 361367-48-8)
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- Floxuridine Impurity 1 (CAS 955-24-8)
- Uridine-15N2 (CAS 92487-68-8)
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- 6-Bromo-2-(pyridin-4-yl)pyridazin-3(2h)-one (CAS 2251053-53-7)
- 1-(pyridin-3-yl)cyclohexane-1-carboxylic acid (CAS 143619-73-2)
- Ni in water quality (CAS CATO-CQCM102211)
- 5-((6-(Trifluoromethyl)pyridin-3-yl)methyl)thiazol-2-amine (CAS 1169491-06-8)
- Benzyl (R)-2-(chloromethyl)pyrrolidine-1-carboxylate (CAS 1187932-05-3)
- Octahydro-1,3-dioxo-2H-isoindole-2-acetic acid (CAS 138220-90-3)
- 6,7,8,9-Tetrahydro-5H-cyclohepta[b]pyridin-3-ol (CAS 1378823-03-0)
- 1-Bromo-4-iodo-2,3-dimethylbenzene (CAS 1160573-43-2)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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