2-(Difluoromethyl)-1,4-bis(trifluoromethyl)benzene CAS 393-83-9
| CAS No. | 393-83-9 |
| Molecular Formula | C9H4F8 |
| Molecular Weight | 264.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Difluoromethyl)-1,4-bis(trifluoromethyl)benzene.
CATO supplies 2-(Difluoromethyl)-1,4-bis(trifluoromethyl)benzene (CAS 393-83-9), a certified reference material (molecular formula C9H4F8, MW 264.12 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H4F8, 2-(Difluoromethyl)-1,4-bis(trifluoromethyl)benzene contains fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 264.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H4F8 |
| Molecular Weight | 264.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3,5-bis(trifluoromethyl)benzene (CAS 1214388-66-5)
- 2-(3-(Difluoromethyl)-5,5-difluoro-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetic acid (CAS 1417982-54-7)
- 7-((Difluoromethyl)sulfonyl)-4-fluoro-2,3-dihydro-1H-inden-1-one (CAS 1672661-81-2)
- 3-[5-(difluoromethyl)-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1018151-04-6)
- 3-[7-(difluoromethyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1018053-30-9)
- 4-(Difluoromethyl)-6-(3,4-dimethylphenyl)-2-hydrazinylpyrimidine (CAS 861225-97-0)
- (E)-2-((difluoromethyl)thio)-4-styrylpyrimidine (CAS 338393-15-0)
- 2-(Difluoromethyl)-4,6-difluoropyridine-3-sulfonyl chloride (CAS 1805282-15-8)
Recommended Standards
- 2-(Benzyloxy)-5-bromopyridine (CAS 83664-33-9)
- 2,2,3,3-Tetrafluoropropyl trifluoromethanesulfonate (CAS 6401-02-1)
- 2-(Benzyloxy)-4-bromopyridine (CAS 960298-00-4)
- 2-{5-bromopyrrolo[2,1-f][1,2,4]triazin-2-yl}acetic acid (CAS 2091480-93-0)
- (5-((4-(tert-Butoxycarbonyl)piperazin-1-yl)methyl)-2-fluorophenyl)boronic acid (CAS 1190095-09-0)
- 1-(2-(2,4-Dimethylphenoxy)ethyl)-1H-pyrazole (CAS 956574-26-8)
- 5F-MDMB-PINACA (5F-ADB) (CAS 1838134-16-9)
- 5-Bromo-Uridine-5-monophosphate disodium salt (CAS 2149-79-3)
- 1-(1,5-Dimethyl-1H-pyrazol-4-yl)-N-((5-fluorothiophen-2-yl)methyl)methanamine hydrochloride (CAS 1856033-76-5)
- N-(5-(Thiophen-3-yl)-1,3,4-oxadiazol-2-yl)isoxazole-5-carboxamide (CAS 1251692-40-6)
- 7-Chloro-1-(3-nitrophenyl)heptan-1-one (CAS 898768-50-8)
- 5-Bromo-2,4-dihydroxybenzoic acid (CAS 7355-22-8)
- (S)-tert-Butyl 1-(3-fluoro-2-nitrophenyl)pyrrolidin-3-ylcarbamate (CAS 1233860-31-5)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com