3-Fluoro-N'-((5-nitrothiophen-2-yl)methylene)benzohydrazide CAS 394694-98-5
| CAS No. | 394694-98-5 |
| Molecular Formula | C12H8FN3O3S |
| Molecular Weight | 293.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Fluoro-N'-((5-nitrothiophen-2-yl)methylene)benzohydrazide (C12H8FN3O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 3-Fluoro-N'-((5-nitrothiophen-2-yl)methylene)benzohydrazide (CAS 394694-98-5), a certified reference material (molecular formula C12H8FN3O3S, MW 293.27 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8FN3O3S |
| Molecular Weight | 293.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
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- 3-Fluoro-N,N-diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2121511-42-8)
- N-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-1-amine (CAS 2377609-37-3)
- N-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-2-amine (CAS 2377607-41-3)
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Recommended Standards
- 3-Amino-4-fluoro-1-(4-fluorophenyl)-1H-indene-1,2-dicarbonitrile (CAS 303150-48-3)
- 4-(2,5-Dioxo-3-phenyl-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid (CAS 33753-36-5)
- 3-(Benzo[d][1,3]dioxole-5-carbonyl)quinolin-4(1H)-one (CAS 769972-66-9)
- 4-(Benzo[d][1,3]dioxol-5-ylmethylene)-2-phenyloxazol-5(4H)-one (CAS 6412-89-1)
- 2-Oxabicyclo[3.1.0]Hexan-6-amine (CAS 1708160-40-0)
- 7-methyl-8-oxa-5-azaspiro[3.5]nonane (CAS 1955540-56-3)
- 3-Amino-1-(3,4-dimethoxybenzyl)-4-(2-fluorophenyl)azetidin-2-one (CAS 1291489-45-6)
- 3-(2-Chlorophenyl)-3-hydroxypropanoic acid (CAS 121669-89-4)
- 3-Amino-N-(2-chloro-phenyl)-4-morpholin-4-yl-benzenesulfonamide (CAS 326023-05-6)
- Dolasetron Impurity 3 (CAS CATO-C4X-18673)
- cyclopropanesulfonyl fluoride 822-49-1 VS-0001 (CAS 822-49-1)
- Ethyl 4-amino-1H-imidazole-5-carboxylate (CAS 21190-16-9)
- Bis(3-fluorophenyl)amine (CAS 333-53-9)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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