2-Chloro-4-methoxynicotinoyl chloride CAS 394729-97-6
| CAS No. | 394729-97-6 |
| Molecular Formula | C7H5Cl2NO2 |
| Molecular Weight | 206.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-methoxynicotinoyl chloride.
2-Chloro-4-methoxynicotinoyl chloride (CAS 394729-97-6) is a high-purity analytical reference standard with the molecular formula C7H5Cl2NO2 and a molecular weight of 206.03 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2-Chloro-4-methoxynicotinoyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 206.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-4-methoxynicotinoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5Cl2NO2 |
| Molecular Weight | 206.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-methoxypyridine-3-carbonyl chloride (CAS 1073230-28-0)
- 2-Chloro-1-(chloromethyl)-3-nitrobenzene (CAS 108772-93-6)
- 116853-97-5 2-Chloro-6-methoxyisonicotinoyl chloride 2-Chloro-6-methoxypyridine-4-carbonyl chloride ZLD0464 zlchem 998 (CAS 116853-97-5)
- 3-Chloro-6-methoxypicolinoyl chloride (CAS 1257535-51-5)
- 3-Chloro-2-nitrobenzyl chloride (CAS 1261642-82-3)
- 2-Chloro-N-(6-chloropyrazin-2-yl)acetamide (CAS 1417793-45-3)
- 1-Chloro-2-(chloromethyl)-3-nitrobenzene (CAS 15258-72-7)
- 2-Chloro-1-(chloromethyl)-4-nitrobenzene (CAS 50274-95-8)
Recommended Standards
- 2-Chloro-N-(2-chloropyrimidin-5-yl)acetamide (CAS 856976-11-9)
- 2-Amino-4,5-dichlorobenzoic Acid (CAS 20776-61-8)
- 3,5-Dichloro-4-hydroxybenzamide (CAS 3337-60-8)
- 2-Amino-3,6-dichlorobenzoic acid (CAS 3032-32-4)
- 5-(tert-Butyl)pyrimidine-2,4(1H,3H)-dione (CAS 17432-97-2)
- 9-(Chloroacetyl)-2,3,4,9-tetrahydro-1h-carbazole (CAS 43170-54-3)
- 4-(5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-2-yl)morpholine (CAS 929973-62-6)
- 5-(Hex-1-yn-1-yl)furan-2-carboxylic acid (CAS 845266-30-0)
- 4-Amino-2,6-dichlorobenzonitrile (CAS 6575-18-4)
- Cenobamate Impurity 28 (CAS 220902-32-9)
- 2-Methyl-3-phenylpropan-1-ol (CAS 7384-80-7)
- (S)-3-Acetyl-1-Boc-pyrrolidine (CAS 1374673-89-8)
- H-Ala-Pro-Val-5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid (CAS 396077-59-1)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com