2-Methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 395063-57-7
| CAS No. | 395063-57-7 |
| Molecular Formula | C5H5N3OS |
| Molecular Weight | 155.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one.
2-Methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 395063-57-7), molecular formula C5H5N3OS and molecular weight 155.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (C5H5N3OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5N3OS |
| Molecular Weight | 155.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylthiazolo Standards
- 3-Methylthiazolo[5,4-d]isoxazol-5-amine (CAS 1706464-22-3)
- 6-Methylthiazolo[3,2-b][1,2,4]triazol-2-amine (CAS 62032-91-1)
- 2-Methylthiazolo[5,4-d]pyrimidine (CAS 13554-88-6)
- 5-Methylthiazolo[5,4-d]pyrimidine (CAS 13554-89-7)
- 2-Methylthiazolo[4,5-b]pyrazine (CAS 87444-21-1)
- 4-Methylthiazolo[4,5-c]pyridine (CAS 1208988-06-0)
- 2-Methylthiazolo[5,4-b]pyridine (CAS 91813-40-0)
- 2-Methylthiazolo[5,4-c]pyridine (CAS 98383-10-9)
Recommended Standards
- 2-[(5-Amino-1H-1,2,4-triazol-3-yl)sulfanyl]-acetonitrile (CAS 338751-47-6)
- 3-Methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-amine (CAS 3176-51-0)
- 2-(5-methoxy-1,3,4-thiadiazol-2-yl)acetonitrile (CAS 84389-19-5)
- 5-Aminoimidazo[2,1-b]thiazol-6-ol (CAS 863203-50-3)
- (4-Chloro-2-fluorophenyl)methanamine hydrochloride (CAS 202982-63-6)
- 3-[(2-methylphenyl)amino]propanoic acid (CAS 23947-32-2)
- 3-Amino-2-fluoro-4-methoxybenzoic acid (CAS 1785489-75-9)
- 6-Amino-2,3-dimethylquinoxaline-5,8-dione (CAS 7697-90-7)
- 1,2-dihydropyrazolo[4,3-c]pyridin-3-one (CAS 3268-73-3)
- (3R,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione (CAS 75112-74-2)
- 5,6,7,8-Tetrahydro-1,6-naphthyridine, oxalic acid (CAS 1193388-00-9)
- 3-hydroxyisoquinoline-8-carboxylic acid (CAS 1337881-30-7)
- 4-Fluoro-2-((hexyloxy)methyl)benzaldehyde (CAS 1443350-84-2)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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