1-Hydroxy-2,5-dioxopyrrolidine-3-carbaldehyde CAS 39508-63-9
| CAS No. | 39508-63-9 |
| Molecular Formula | C5H5NO4 |
| Molecular Weight | 143.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Hydroxy-2,5-dioxopyrrolidine-3-carbaldehyde (CAS 39508-63-9) is a high-purity analytical reference standard with the molecular formula C5H5NO4 and a molecular weight of 143.10 g/mol.
The molecular framework of 1-Hydroxy-2,5-dioxopyrrolidine-3-carbaldehyde (C5H5NO4) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5NO4 |
| Molecular Weight | 143.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1-Methyl-5-nitro-1,3-dihydro-2H-imidazol-2-one (CAS 63062-13-5)
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- 1-(4-Amino-6-chloropyrimidin-5-yl)ethanone (CAS 1620842-91-2)
- 3-(4-Chlorophenyl)-5-(piperidin-4-yl)-1,2,4-oxadiazole (CAS 276236-98-7)
- Rimegepant Impurity 65 (CAS CATO-C4X-248765)
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- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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