4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine CAS 396-63-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine.

4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine (CAS 396-63-4) is a high-purity analytical reference standard with the molecular formula C9H6F3N3S and a molecular weight of 245.22 g/mol.

4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine (C9H6F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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