Chloramphenicol glucuronide CAS 39751-33-2
| CAS No. | 39751-33-2 |
| Molecular Formula | C17H20Cl2N2O11 |
| Molecular Weight | 499.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Chloramphenicol glucuronide (CAS 39751-33-2) is a high-purity analytical reference standard with the molecular formula C17H20Cl2N2O11 and a molecular weight of 499.25 g/mol.
Chloramphenicol glucuronide (C17H20Cl2N2O11) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H20Cl2N2O11 |
| Molecular Weight | 499.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloramphenicol Standards
- Chloramphenicol 1-O-β-D-Glucuronide (CAS 1013074-93-5)
- Chloramphenicol ß-D-galactoside (CAS 191476-32-1)
- Chloramphenicol 2-(O-tert-Butyldimethylsilyl)methyl 1-Acetate (CAS 864529-27-1)
- Chloramphenicol O-tert-Butyldimethylsilyl Ether (CAS 864529-25-9)
- Chloramphenicol Palmitate (CAS 530-43-8)
- Chloramphenicol 3-Acetate (CAS 10318-16-8)
- Chloramphenicol 1-Acetate (CAS 23214-93-9)
- Chloramphenicol Impurity 18 (CAS 40027-72-3)
Recommended Standards
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- N-[2,4-Dichloro-5-(2-methoxyethoxy)phenyl]-3-[(2,6-dichlorophenyl)sulfanyl]-2-hydroxy-2-methylpropanamide (CAS 866130-96-3)
- (Cyanomethyl)(triphenylphosphine)gold (CAS 90142-80-6)
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- 1-((4-Methoxynaphthalen-1-yl)methyl)urea (CAS 102613-42-3)
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