4-chloro-5-iodopyrimidin-2-amine CAS 3993-80-4
| CAS No. | 3993-80-4 |
| Molecular Formula | C4H9ClIN3 |
| Molecular Weight | 261.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 261.49 g/mol gives 4-chloro-5-iodopyrimidin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-chloro-5-iodopyrimidin-2-amine (CAS 3993-80-4), molecular formula C4H9ClIN3 and molecular weight 261.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-chloro-5-iodopyrimidin-2-amine (C4H9ClIN3) is characterized by chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-chloro-5-iodopyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H9ClIN3 |
| Molecular Weight | 261.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 4-Chloro-2-iodopyridin-3-ol (CAS 188057-56-9)
- 2-chloro-5-iodopyrimidin-4-amine (CAS 597551-56-9)
- 6-chloro-5-iodopyrimidin-4-amine (CAS 353272-15-8)
- 2-Chloro-6-(4,5-dichloro-1H-pyrrol-3-yl)aniline (CAS 124201-43-0)
- 2-Chloro-6-(difluoromethyl)-4-methoxy-3-(trifluoromethyl)pyridine (CAS 1804370-69-1)
- (2-Chloro-4-(difluoromethyl)-5-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1804380-74-2)
- 2-Chloro-4-(difluoromethyl)-3-methoxy-5-(trifluoromethyl)pyridine (CAS 1804664-20-7)
- (2-Chloro-5-(difluoromethyl)-3-(trifluoromethyl)pyridin-4-yl)methanol (CAS 1804716-95-7)
Recommended Standards
- 2-chlorophenyl dichloro(sulfanylidene)phosphinite (CAS 68591-34-4)
- (E)-3-(4-Bromo-3-chlorophenyl)acrylic acid (CAS 1022081-97-5)
- 2,4,5-Trichloro-6-Methoxyisophthalonitrile (CAS 57531-87-0)
- 5-Bromo-2,3-dihydrobenzo[b]-furan-7-carbonyl chloride (CAS 108551-60-6)
- tert-Butyl 4-(azetidin-3-yl)piperazine-1-carboxylate dihydrochloride (CAS 1803566-76-8)
- 2-(1-(4-Bromobenzyl)piperidin-3-yl)-1H-benzo[d]imidazole (CAS 887218-37-3)
- n-(3-(n,n-Dimethylsulfamoyl)phenyl)hydrazinecarbothioamide (CAS 726153-42-0)
- (2R,3S)-3-Amino-2-methylbutanoic acid (CAS 39801-26-8)
- 6-((tert-Butoxycarbonyl)amino)-2-naphthoic acid (CAS 516465-99-9)
- Ethyl 3-acetamido-4-cyclopropyl-4-oxobutanoate (CAS 1823601-07-5)
- 1H-imidazol-5-ol (CAS 71713-86-5)
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