(E)-4,4,4-trifluoro-3-methylbut-2-enoic acid CAS 400-28-2

Description

Compared with other compounds in its class, the molecular weight of 154.09 g/mol gives (E)-4,4,4-trifluoro-3-methylbut-2-enoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(E)-4,4,4-trifluoro-3-methylbut-2-enoic acid (CAS 400-28-2) is a high-purity analytical reference standard with the molecular formula C5H5F3O2 and a molecular weight of 154.09 g/mol.

The molecular framework of (E)-4,4,4-trifluoro-3-methylbut-2-enoic acid (C5H5F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com