5-Chloro-2,4-bis(trifluoromethyl)pyridine CAS 400-79-3
| CAS No. | 400-79-3 |
| Molecular Formula | C7H2ClF6N |
| Molecular Weight | 249.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2,4-bis(trifluoromethyl)pyridine is closely related to a nitrile group, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-2,4-bis(trifluoromethyl)pyridine (CAS 400-79-3), a certified reference material (molecular formula C7H2ClF6N, MW 249.54 g/mol) for analytical method development and quality control.
5-Chloro-2,4-bis(trifluoromethyl)pyridine (C7H2ClF6N) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H2ClF6N |
| Molecular Weight | 249.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4,5-bis(trifluoromethyl)pyridine (CAS 109919-25-7)
- 4-Chloro-3,5-bis-trifluoromethyl-pyridine (CAS 1286743-85-8)
- 6-chloro-2,3-bis(trifluoromethyl)pyridine (CAS 153617-04-0)
- 2-Chloro-3,6-bis(trifluoromethyl)pyridine (CAS 175136-26-2)
- 5-Chloro-2,3-bis(trifluoromethyl)pyridine (CAS 1804142-23-1)
- 2-Chloro-6-(difluoromethyl)-3-fluoro-5-(trifluoromethyl)pyridine (CAS 1805262-33-2)
- 3-Chloro-2,5-bis(trifluoromethyl)pyridine (CAS 1806500-17-3)
- 2-Chloro-3,5-bis(trifluoromethyl)pyridine (CAS 70158-60-0)
Recommended Standards
- 4-Chloro-2,6-bis(trifluoromethyl)pyridine (CAS 81269-96-7)
- 5-bromopentane-1-sulfonyl chloride (CAS 213774-63-1)
- 3-Chloro-2,6-bis(trifluoromethyl)pyridine (CAS 400-80-6)
- 6-Chloro-4-(trifluoromethyl)indoline-2,3-dione (CAS 1332605-88-5)
- 4-Hydroxy-quinoline-3-carboxylic Acid 34785-11-0 MFCD00598887 SY003660 (CAS 34785-11-0)
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- 2-Amino-4-iodopyridine (CAS 552331-00-7)
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