4-Chloro-N-methyl-5-(methylthio)-6-(pyrrolidin-1-yl)pyrimidin-2-amine CAS 400074-29-5
| CAS No. | 400074-29-5 |
| Molecular Formula | C10H15ClN4S |
| Molecular Weight | 258.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-N-methyl-5-(methylthio)-6-(pyrrolidin-1-yl)pyrimidin-2-amine.
4-Chloro-N-methyl-5-(methylthio)-6-(pyrrolidin-1-yl)pyrimidin-2-amine (CAS 400074-29-5) is a high-purity analytical reference standard with the molecular formula C10H15ClN4S and a molecular weight of 258.77 g/mol.
The molecular framework of 4-Chloro-N-methyl-5-(methylthio)-6-(pyrrolidin-1-yl)pyrimidin-2-amine (C10H15ClN4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-N-methyl-5-(methylthio)-6-(pyrrolidin-1-yl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15ClN4S |
| Molecular Weight | 258.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- (3-(Furan-2-yl)-3-phenylprop-1-yn-1-yl)trimethylsilane (CAS 919283-69-5)
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