6-Chloro-N4-cyclohexyl-N2-methyl-5-(methylthio)pyrimidine-2,4-diamine CAS 400074-34-2

Purity 97%+In StockPharmaceutical Standards
CAS No.400074-34-2
Molecular FormulaC12H19ClN4S
Molecular Weight286.82 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Chloro-N4-cyclohexyl-N2-methyl-5-(methylthio)pyrimidine-2,4-diamine CAS 400074-34-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

6-Chloro-N4-cyclohexyl-N2-methyl-5-(methylthio)pyrimidine-2,4-diamine (CAS 400074-34-2), molecular formula C12H19ClN4S and molecular weight 286.82 g/mol, is a CATO reference standard with documented purity and traceability.

6-Chloro-N4-cyclohexyl-N2-methyl-5-(methylthio)pyrimidine-2,4-diamine (C12H19ClN4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H19ClN4S
Molecular Weight286.82 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms4
Sulfur Atoms1

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