11F-412S 2-[(3-chlorophenyl)methyl]-4-(prop-2-yn-1-ylsulfanyl)quinazoline 400075-32-3 CAS 400075-32-3

Purity 97%+In StockPharmaceutical Standards
CAS No.400075-32-3
Molecular FormulaC18H13ClN2S
Molecular Weight324.83 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

11F-412S 2-[(3-chlorophenyl)methyl]-4-(prop-2-yn-1-ylsulfanyl)quinazoline 400075-32-3 CAS 400075-32-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 324.83 g/mol gives 11F-412S 2-[(3-chlorophenyl)methyl]-4-(prop-2-yn-1-ylsulfanyl)quinazoline 400075-32-3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 11F-412S 2-[(3-chlorophenyl)methyl]-4-(prop-2-yn-1-ylsulfanyl)quinazoline 400075-32-3 (CAS 400075-32-3), a certified reference material (molecular formula C18H13ClN2S, MW 324.83 g/mol) for analytical method development and quality control.

The molecular framework of 11F-412S 2-[(3-chlorophenyl)methyl]-4-(prop-2-yn-1-ylsulfanyl)quinazoline 400075-32-3 (C18H13ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 11F-412S 2-[(3-chlorophenyl)methyl]-4-(prop-2-yn-1-ylsulfanyl)quinazoline 400075-32-3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H13ClN2S
Molecular Weight324.83 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

Recommended Standards

Why CATO?