4-(2,4-Dichlorobenzyl)-8-(4-nitrophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane CAS 400075-71-0
| CAS No. | 400075-71-0 |
| Molecular Formula | C20H21Cl2N3O3 |
| Molecular Weight | 422.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(2,4-Dichlorobenzyl)-8-(4-nitrophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane (CAS 400075-71-0) is a high-purity analytical reference standard with the molecular formula C20H21Cl2N3O3 and a molecular weight of 422.31 g/mol.
4-(2,4-Dichlorobenzyl)-8-(4-nitrophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane (C20H21Cl2N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4-(2,4-Dichlorobenzyl)-8-(4-nitrophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21Cl2N3O3 |
| Molecular Weight | 422.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorobenzyl Standards
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- 3-((2,6-Dichlorobenzyl)thio)-N-(3,4-dimethylphenyl)thiophene-2-carboxamide (CAS 251097-40-2)
- 1-(3,4-Dichlorobenzyl)-2-oxo-6-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carbonitrile (CAS 252059-82-8)
- 3-((2,4-Dichlorobenzyl)oxy)-N-(4-nitrophenyl)thiophene-2-carboxamide (CAS 339098-07-6)
- 3-(4-((2,4-Dichlorobenzyl)oxy)phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 1234691-94-1)
- 2-(4-((3,4-Dichlorobenzyl)oxy)phenyl)-4-(p-tolyl)pyrimidine (CAS 477846-92-7)
- N-(1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methylbenzenesulfonamide (CAS 400086-24-0)
Recommended Standards
- 2-((2-Methoxyphenyl)amino)-2-oxoethyl 3-bromoadamantane-1-carboxylate (CAS 436114-76-0)
- Benzyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine-1-carboxylate (CAS 1150561-68-4)
- (2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-(4-methylphenyl)prop-2-enamide (CAS 477889-45-5)
- Ethyl N-(tert-butoxycarbonyl)-S-(3,5-dichlorobenzoyl)cysteinate (CAS 1192667-96-1)
- 2-(6-Methoxy-2-methylpyridin-3-yl)acetonitrile (CAS 853569-73-0)
- 2-Bromo-3-thiocyanatoprop-1-ene (CAS 102367-26-0)
- 4-Amino-2,2-dioxoisothiochromane Hydrochloride (CAS 1187830-61-0)
- 1,2,3-Trifluoro-4-methoxybenzene (CAS 203245-16-3)
- Brexpiprazole Impurity 129 (CAS CATO-C4X-1131129)
- Ethyl 2-[2-(2-fluorophenyl)-1,3-thiazol-4-yl]acetate (CAS 842113-80-8)
- 1-Chloro-2-fluoro-3-((methylsulfonyl)methyl)benzene (CAS 886498-11-9)
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- 948291-38-1 2-Chloro-3-(chloromethyl)-7-fluoroquinoline DTXSID10588985 (CAS 948291-38-1)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
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