2-{[5-(4-chlorobenzoyl)thiophen-2-yl]methyl}-4-(4-chlorophenyl)-1,3-thiazole CAS 400075-83-4
| CAS No. | 400075-83-4 |
| Molecular Formula | C21H13Cl2NOS2 |
| Molecular Weight | 430.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-{[5-(4-chlorobenzoyl)thiophen-2-yl]methyl}-4-(4-chlorophenyl)-1,3-thiazole (C21H13Cl2NOS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-{[5-(4-chlorobenzoyl)thiophen-2-yl]methyl}-4-(4-chlorophenyl)-1,3-thiazole (CAS 400075-83-4) is a high-purity analytical reference standard with the molecular formula C21H13Cl2NOS2 and a molecular weight of 430.37 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-{[5-(4-chlorobenzoyl)thiophen-2-yl]methyl}-4-(4-chlorophenyl)-1,3-thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H13Cl2NOS2 |
| Molecular Weight | 430.37 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related chlorobenzoyl Standards
- 2-(4-Chlorobenzoyl)-3-[(2-chlorobenzenesulfinyl)methyl]-1-benzofuran (CAS 338424-32-1)
- 2-(4-Chlorobenzoyl)-3-[(4-chlorobenzenesulfinyl)methyl]-1-benzofuran (CAS 338423-85-1)
- 3-[1-(3-Chlorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775385-40-4)
- 3-[1-(2-Chlorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775513-23-9)
- 5-(4-Chlorobenzoyl)-N,N-dimethyl-3-(4-phenoxyphenyl)thiophen-2-amine (CAS 338976-24-2)
- 3-(4-Chlorobenzoyl)-4-[5-(2,4-dichlorophenyl)furan-2-yl]-1-methylpyrrolidine (CAS 478050-11-2)
- 4-(4-Chlorobenzoyl)-1-[(3-chlorophenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-32-5)
- 4-(4-Chlorobenzoyl)-1-[(4-chlorophenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-27-8)
Recommended Standards
- 2-(3-(Trifluoromethyl)benzyl)-N-(3-(trifluoromethyl)phenyl)thiazole-4-carboxamide (CAS 478042-41-0)
- 4-Methyl-N,2-bis(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 320420-95-9)
- 2-(3-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 692287-82-4)
- 6-Methyl-2-oxo-2H-pyran-4-yl (2E)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enoate (CAS 866151-68-0)
- Methyl 3-hexyl-3-methyloxirane-2-carboxylate (CAS 1483371-45-4)
- Methyl 5-(((1-bromonaphthalen-2-yl)oxy)methyl)furan-2-carboxylate (CAS 832738-12-2)
- 1-(2-Bromo-4-fluorobenzyl)-1h-pyrazol-4-amine (CAS 1152940-27-6)
- methyl 4-methyl-5-oxo-4,5-dihydropyrazine-2-carboxylate (CAS 1416447-68-1)
- 3-Chloro-4-(2-(trifluoromethyl)phenyl)-1H-pyrrole (CAS 88594-17-6)
- 2-(benzo[d]thiazol-2-yl)acetonitrile (CAS 56278-50-3)
- (S)-3-Acetyl-4-hydroxy-5-methyl-1H-pyrrol-2(5H)-one (CAS 128948-45-8)
- N-Cyclopentyl-2-[[2-(4-Fluorophenyl)-6-Methyl-4-Quinazolinyl]Thio]-Acetamide (CAS 606131-34-4)
- 1-Chloro-3,7-dimethylisoquinoline (CAS 1206971-18-7)
- Semaglutide Impurity 5 (CAS 23406-82-8)
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