2-Chlorophenyl 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylate CAS 400079-26-7

Purity 97%+In StockPharmaceutical Standards
CAS No.400079-26-7
Molecular FormulaC14H9ClN4O2
Molecular Weight300.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chlorophenyl 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylate CAS 400079-26-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chlorophenyl 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylate.

2-Chlorophenyl 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylate (CAS 400079-26-7), molecular formula C14H9ClN4O2 and molecular weight 300.70 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Chlorophenyl 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylate (C14H9ClN4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chlorophenyl 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H9ClN4O2
Molecular Weight300.70 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms4

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