3-(2,4-Dichlorophenoxymethyl)-1h-1,2,4-triazole-5-carboxamide CAS 400080-22-0
| CAS No. | 400080-22-0 |
| Molecular Formula | C10H8Cl2N4O2 |
| Molecular Weight | 287.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2,4-Dichlorophenoxymethyl)-1h-1,2,4-triazole-5-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(2,4-Dichlorophenoxymethyl)-1h-1,2,4-triazole-5-carboxamide (CAS 400080-22-0), a certified reference material (molecular formula C10H8Cl2N4O2, MW 287.10 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2,4-Dichlorophenoxymethyl)-1h-1,2,4-triazole-5-carboxamide (C10H8Cl2N4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2,4-Dichlorophenoxymethyl)-1h-1,2,4-triazole-5-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8Cl2N4O2 |
| Molecular Weight | 287.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichlorophenoxymethyl Standards
- 5-(2,4-Dichlorophenoxymethyl)furan-2-carboxylic acid (CAS 74556-60-8)
- 5-(2,6-dichlorophenoxymethyl)-1,2-oxazole-3-carboxylic acid (CAS 1225900-23-1)
- 5-(2,4-Dichlorophenoxymethyl)-1,2-oxazole-3-carboxylic acid (CAS 932894-91-2)
- 5-(2,4-Dichlorophenoxymethyl)-1,3,4-oxadiazole-2-thiol (CAS 50848-29-8)
- 2-(2,3-dichlorophenoxymethyl)benzoic acid (CAS 938124-26-6)
- 4-(2,5-Dichlorophenoxymethyl)-1,3-thiazol-2-amine (CAS 1082303-05-6)
- 4-(2,4-Dichlorophenoxymethyl)-1,3-thiazol-2-amine (CAS 612802-16-1)
- 5-(2,3-Dichlorophenoxymethyl)furan-2-carbaldehyde (CAS 438219-17-1)
Recommended Standards
- 2-Bromo-4-trifluoromethoxythioanisole (CAS 951884-71-2)
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- 3-(3-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 30149-95-2)
- 4-Bromo-5-methyl-1H-indazole (CAS 926922-40-9)
- 5-Amino-1-(2-hydroxyethyl)pyrazole-4-carboxylic Acid (CAS 58046-50-7)
- 7-bromo-1H-pyrrolo[3,2-c]pyridine (CAS 902837-42-7)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
- 2-(5-Chloro-2-methoxyphenyl)propan-2-amine hydrochloride (CAS 1909348-43-1)
- 898766-21-7 1-(2,3-Dimethylphenyl)-2,2-dimethylpropan-1-one DTXSID80611198 (CAS 898766-21-7)
- N-(4-Bromobenzyl)-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-2-amine (CAS 1251707-85-3)
- 7-Hydroxy-3-(naphthalen-2-yloxy)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 371128-42-6)
- 3-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(4-hydroxybenzylidene)propanehydrazide (CAS 478530-52-8)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
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