Prop-2-yn-1-yl 6-(1H-1,2,4-triazol-1-yl)nicotinate CAS 400080-47-9

Purity 97%+In StockPharmaceutical Standards
CAS No.400080-47-9
Molecular FormulaC11H8N4O2
Molecular Weight228.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Prop-2-yn-1-yl 6-(1H-1,2,4-triazol-1-yl)nicotinate CAS 400080-47-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 228.21 g/mol gives Prop-2-yn-1-yl 6-(1H-1,2,4-triazol-1-yl)nicotinate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Prop-2-yn-1-yl 6-(1H-1,2,4-triazol-1-yl)nicotinate (CAS 400080-47-9) is a high-purity analytical reference standard with the molecular formula C11H8N4O2 and a molecular weight of 228.21 g/mol.

Prop-2-yn-1-yl 6-(1H-1,2,4-triazol-1-yl)nicotinate (C11H8N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Prop-2-yn-1-yl 6-(1H-1,2,4-triazol-1-yl)nicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8N4O2
Molecular Weight228.21 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms4

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