(E)-N-((2-(2-chlorophenyl)hydrazono)methyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide CAS 400081-41-6

Purity 97%+In StockPharmaceutical Standards
CAS No.400081-41-6
Molecular FormulaC18H14ClF6N3O3
Molecular Weight469.77 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-N-((2-(2-chlorophenyl)hydrazono)methyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide CAS 400081-41-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-N-((2-(2-chlorophenyl)hydrazono)methyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide.

CATO supplies (E)-N-((2-(2-chlorophenyl)hydrazono)methyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 400081-41-6), a certified reference material (molecular formula C18H14ClF6N3O3, MW 469.77 g/mol) for analytical method development and quality control.

Structurally, (E)-N-((2-(2-chlorophenyl)hydrazono)methyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (C18H14ClF6N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 469.77 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H14ClF6N3O3
Molecular Weight469.77 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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