4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,6-bis(trifluoromethyl)pyridine CAS 400081-58-5

Purity 97%+In StockPharmaceutical Standards
CAS No.400081-58-5
Molecular FormulaC12H9F6N3
Molecular Weight309.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,6-bis(trifluoromethyl)pyridine CAS 400081-58-5 chemical structure

Description

The molecular framework of 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,6-bis(trifluoromethyl)pyridine (C12H9F6N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO supplies 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,6-bis(trifluoromethyl)pyridine (CAS 400081-58-5), a certified reference material (molecular formula C12H9F6N3, MW 309.21 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,6-bis(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H9F6N3
Molecular Weight309.21 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3

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