1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2-oxo-N-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide CAS 400083-13-8
| CAS No. | 400083-13-8 |
| Molecular Formula | C22H15F5N2O4 |
| Molecular Weight | 466.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2-oxo-N-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (C22H15F5N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2-oxo-N-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (CAS 400083-13-8), molecular formula C22H15F5N2O4 and molecular weight 466.36 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2-oxo-N-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H15F5N2O4 |
| Molecular Weight | 466.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzo Standards
- 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2-oxo-N-(2-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide (CAS 400082-68-0)
- 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide (CAS 400082-69-1)
- N-(4,6-Difluorobenzo[d]thiazol-2-yl)-1-(thiophen-2-ylsulfonyl)piperidine-3-carboxamide (CAS 921504-28-1)
- 4,4'-((5,6-Difluorobenzo[c][1,2,5]thiadiazole-4,7-diyl)bis(ethyne-2,1-diyl))dibenzaldehyde (CAS 2460375-95-3)
- 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-N-(2-methoxybenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400083-06-9)
- 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-N-(2,6-dimethylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400082-72-6)
- 2-(1-((5,7-Difluorobenzo[d]thiazol-2-yl)methyl)-4,5-dimethyl-6-oxo-1,6-dihydropyridazin-3-yl)acetic acid (CAS 140926-46-1)
- N-(4,6-Difluorobenzo[d]thiazol-2-yl)-2-(ethylthio)benzamide (CAS 886917-65-3)
Recommended Standards
- 2,5-Dibromo-3-hexadecylthiophene (CAS 178452-13-6)
- Disodium 4,4'-Diazidostilbene-2,2'-disulfonate Tetrahydrate (CAS 2718-90-3)
- N-(3,4-Dimethylisoxazol-5-yl)-N-((2-methoxyethoxy)methyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 176961-13-0)
- N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-3-propionamidobenzamide (CAS 881795-95-5)
- Methyl 6-Isoquinolinecarboxylate (CAS 173089-82-2)
- 2-[(4-Bromophenyl)sulfanyl]-6-phenyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338749-49-8)
- 1-(2-(Trifluoromethyl)benzyl)-1h-imidazole-2-carboxylic acid (CAS 1439903-16-8)
- 2-({[4-(3-bromophenyl)-1,3-thiazol-2-yl]methyl}amino)ethan-1-ol (CAS 1803607-76-2)
- 4-Cyclopropoxy-3-methoxy-N-methylpyridin-2-amine (CAS 1243354-54-2)
- 4-Acetyl-3-methyl-1-phenyl-1H-pyrazol-5-yl acetate (CAS 64360-23-2)
- Ethyl 5-(aminomethyl)-1H-pyrrole-2-carboxylate (CAS 887777-20-0)
- 4-Chloro-6-hydroxypyrimidine (CAS 4765-77-9)
- {2-[(4-methylphenyl)sulfanyl]pyridin-3-yl}methyl N-(3-chlorophenyl)carbamate (CAS 478031-16-2)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
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