4-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]benzonitrile CAS 400083-79-6
| CAS No. | 400083-79-6 |
| Molecular Formula | C15H8ClF3N2 |
| Molecular Weight | 308.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]benzonitrile (C15H8ClF3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]benzonitrile (CAS 400083-79-6), a certified reference material (molecular formula C15H8ClF3N2, MW 308.69 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H8ClF3N2 |
| Molecular Weight | 308.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 4-Chloro-2-(4-(trifluoromethyl)phenyl)quinazoline (CAS 1041568-57-3)
- 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)quinazoline (CAS 1241914-82-8)
- 6-Chloro-2-(4-(trifluoromethyl)phenyl)quinoxaline (CAS 1391118-27-6)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-N-((dimethylamino)methylene)acetamide (CAS 303148-19-8)
- 2-chloro-1-{4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-one (CAS 278791-54-1)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamide (CAS 339029-21-9)
- 4-chloro-2-[2-(trifluoromethyl)phenyl]quinazoline (CAS 404827-94-7)
- 1-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid (CAS 1208081-19-9)
Recommended Standards
- N-(4-chlorobenzyl)-3-fluoro-4-nitrobenzamide (CAS 1485624-57-4)
- 1-(2-Chloro-5-fluoro-4-pyrimidinyl)-4-(methoxymethyl)-6-methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile (CAS 1266375-73-8)
- 3-(4-Chloro-3-nitrobenzenesulfonamido)propanoic acid (CAS 81473-68-9)
- Bumetanide Impurity 74 (CAS CATO-C4X-198674)
- N-(2-((tetrahydro-2H-thiopyran-4-yl)amino)ethyl)cyclopropanecarboxamide (CAS 1597255-23-6)
- Dimethyl (R)-2,2'-dihydroxy-[1,1'-binaphthalene]-3,3'-dicarboxylate (CAS 18531-91-4)
- 2-Bromo-1-(pyridin-2-yl)butan-1-one (CAS 1199773-08-4)
- (R)-2,2,2-Trifluoro-1-((S)-pyrrolidin-2-yl)ethanol (CAS 1044740-42-2)
- tert-Butyl 5-(hydroxymethyl)-3,4-dihydro-2,7-naphthyridine-2(1H)-carboxylate (CAS 1250999-83-7)
- Cholesteryl 2-naphthoate (CAS 63520-67-2)
- (3-(Diphenylphosphoryl)phenyl)boronic acid (CAS 1437305-40-2)
- 4-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonylchloride (CAS 885950-90-3)
- 2-(Chloromethyl)-4-cyano-3-(difluoromethyl)-5-hydroxypyridine (CAS 1804495-16-6)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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