2,6-Dimethylpyrimidin-4-yl 2-chloro-6-fluorobenzoate CAS 400083-83-2

Purity 97%+In StockPharmaceutical Standards
CAS No.400083-83-2
Molecular FormulaC13H10ClFN2O2
Molecular Weight280.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-Dimethylpyrimidin-4-yl 2-chloro-6-fluorobenzoate CAS 400083-83-2 chemical structure

Description

As a certified reference material (CRM), 2,6-Dimethylpyrimidin-4-yl 2-chloro-6-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

2,6-Dimethylpyrimidin-4-yl 2-chloro-6-fluorobenzoate (CAS 400083-83-2), molecular formula C13H10ClFN2O2 and molecular weight 280.68 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,6-Dimethylpyrimidin-4-yl 2-chloro-6-fluorobenzoate (C13H10ClFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC13H10ClFN2O2
Molecular Weight280.68 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

Related Dimethylpyrimidin Standards

Recommended Standards

Why CATO?