4-(4-Chlorophenyl)-1-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]-3-methyl-1H-pyrazol-5-amine CAS 400085-58-7
| CAS No. | 400085-58-7 |
| Molecular Formula | C19H18Cl3N3O2 |
| Molecular Weight | 426.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Chlorophenyl)-1-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]-3-methyl-1H-pyrazol-5-amine (C19H18Cl3N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(4-Chlorophenyl)-1-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]-3-methyl-1H-pyrazol-5-amine (CAS 400085-58-7) is a high-purity analytical reference standard with the molecular formula C19H18Cl3N3O2 and a molecular weight of 426.72 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18Cl3N3O2 |
| Molecular Weight | 426.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
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Recommended Standards
- 3,4-Dichloro-N-(2-(4-(4-chlorophenyl)piperazin-1-yl)-2-oxoethyl)benzamide (CAS 338419-59-3)
- Cucurbitadienol (CAS 35012-08-9)
- (6E,10E,14Z,18Z)-2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-ol (CAS 90695-03-7)
- Cycloeucalenol (CAS 469-39-6)
- 2-(2-Bromo-4-fluorophenyl)acetimidamide (CAS 1016721-80-4)
- L-Daunosamine, Hydrochoride (CAS 105497-63-0)
- 4-Methyl-1-(3-(triethylammonio)propyl)pyridin-1-ium bromide (CAS 79916-28-2)
- 2,7-Dimethoxy-quinoline-3-carbaldehyde (CAS 95395-23-6)
- Pitavastatin Impurity 99 (CAS 176593-07-0)
- Ticagrelor Impurity 48 (CAS CATO-C4X-109348)
- 1,3,6-Trimethylpyrrolo[1,2-a]pyrazine (CAS 147674-37-1)
- tert-Butyl (R)-2-(tert-butyl)piperazine-1-carboxylate hydrochloride (CAS 1381958-53-7)
- Ce-UiO-66 (CAS 1801427-51-9)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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