1-Benzhydryl-4-(5-nitropyridin-2-yl)piperazine CAS 400088-77-9
| CAS No. | 400088-77-9 |
| Molecular Formula | C22H22N4O2 |
| Molecular Weight | 374.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Benzhydryl-4-(5-nitropyridin-2-yl)piperazine (C22H22N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-Benzhydryl-4-(5-nitropyridin-2-yl)piperazine (CAS 400088-77-9), a certified reference material (molecular formula C22H22N4O2, MW 374.44 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22N4O2 |
| Molecular Weight | 374.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Benzhydryl Standards
- 1-Benzhydryl-4-(3-nitropyridin-2-yl)piperazine (CAS 400088-91-7)
- 3-Benzhydryl-5-(4-nitrophenoxy)-4,5-dihydroisoxazole (CAS 89249-66-1)
- 1-Benzhydryl-3-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)urea (CAS 1207016-97-4)
- 1-Benzhydryl-3-(5-(thiophen-3-yl)-1,3,4-oxadiazol-2-yl)urea (CAS 1251686-95-9)
- 1-Benzhydryl-3-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)urea (CAS 1797867-16-3)
- 4-Benzhydryl-6-bromo-2-methyl-1,2,4-triazine-3,5(2H,4H)-dione (CAS 20028-49-3)
- 4-Benzhydryl-N-phenylpiperazine-1-carboxamide (CAS 358747-62-3)
- 3-Benzhydryl-5-(4-chloro-2-methylphenoxy)-4,5-dihydroisoxazole (CAS 89249-67-2)
Recommended Standards
- 5-[4-(4-Methylbenzoyl)piperazin-1-yl]-6-phenyl-2,3-dihydropyridazin-3-one (CAS 477863-60-8)
- 1,3-Bis(tert-butyl(pyridin-2-yl)phosphino)propane (CAS 2241012-50-8)
- N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1H-indol-3-yl)propanamide (CAS 742116-45-6)
- 1,1'-(5,5'-Diphenyl-3,3',4,4'-tetrahydro-2H,2'H-[3,3'-bipyrazole]-2,2'-diyl)diethanone (CAS 27825-09-8)
- Ethyl {[2-cyano-5-(trifluoromethyl)-pyridin-3-yl]oxy}acetate (CAS 1992985-72-4)
- 1,2-Diphenyl-1H-benzo[d]imidazo[1,2-a]imidazole (CAS 36289-17-5)
- n,n-Dimethyl-2-(3-methyl-5-sulfanyl-4h-1,2,4-triazol-4-yl)acetamide (CAS 353286-93-8)
- N2-(3-methoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 69025-47-4)
- 2,6-Dichloro-3-(4-fluorobenzyl)pyridine (CAS 58597-06-1)
- (5-(Pyridin-2-yl)thiophen-2-yl)boronic acid (CAS 1370367-42-2)
- 2-[(4-methoxyphenyl)methyl]-2H-1,2,3,4-tetrazole-5-carboxylic acid (CAS 70978-20-0)
- 1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-bromopyrimidine-2,4(1H,3H)-dione (CAS 63660-21-9)
- Ethyl Trifluoroacetate (CAS 383-63-1)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
Why CATO?
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